Published March 1, 2018 | Version v1
Journal article Open

Inflammation and Breast Cancer: A Mini Review

Creators

  • 1. Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana, USA

Description

Chronic inflammation is a critical factor in tumor progression. Adipocyte accumulation and cytokines storm during inflammation have a significant impact on breast cancer. The development of cancer arises from sites of infection, chronic irritation and inflammation. Furthermore, tumor seed in tumor microenvironment as seed and soil, orchestrated by inflammatory cells, is an indispensable for cells transformed into benign or malignancy status and further fostering proliferation, survival, and migration. These insights are fostering new anti-inflammatory therapeutic approaches to cancer development.

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