Published March 1, 2018
| Version v1
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Inflammation and Breast Cancer: A Mini Review
Creators
- 1. Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana, USA
Description
Chronic inflammation is a critical factor in tumor progression. Adipocyte accumulation and cytokines storm during inflammation have a significant impact on breast cancer. The development of cancer arises from sites of infection, chronic irritation and inflammation. Furthermore, tumor seed in tumor microenvironment as seed and soil, orchestrated by inflammatory cells, is an indispensable for cells transformed into benign or malignancy status and further fostering proliferation, survival, and migration. These insights are fostering new anti-inflammatory therapeutic approaches to cancer development.
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