STUDY TO KNOW THE INCIDENCE OF HEPATITIS C VIRUS INFECTION IN PATIENTS HAVING DIABETES MELLITUS

Hepatitis C virus (HCV) is higher significantly present in type 2 diabetes mellitus (DM), regardless of cirrhosis, control, or HBV patients, regardless of the patient with chronic infection. In addition, it significantly increases the DM risk in individuals susceptible to previous HCV infection. Even in patients who are non-diabetics, there is resistance to insulin and in the insulin signaling pathways have specific defects.

Objective: The study to know the incidence of Hepatitis C viral infection in patients having Diabetes Mellitus.

Study Design: A Cross Sectional Study.

Place and Duration: The study was performed in the medicine department of Nishter Hospital, Multan for the Period of one year from April 2016 to April 2017.

 Subject and Method:  From 154 diabetic patients treated in emerging clinical patients was analyzed for HCV antibodies using an enzyme-linked immunosorbent assay (ELISA) commercial second generation.

Findings: 18.83% (n = 29) of 154 diabetic patients were anti-HCV antibodies positive. The high incidence of HCV antibodies in the age of 29 was 41-50%. HCV prevalence in diabetic women was 13.84% in male patients and 22.47% in male patients.

Conclusions: The HCV infection prevalence among diabetic people in Multan is 2-3 times higher than that reported by the Pakistan Medical Research Council (PMRC), compared to normal healthy individuals.

 Key words: Diabetes mellitus, HCV.