Published June 8, 2018 | Version v1
Journal article Open

Exploring the influence from whole blood DNA extraction methods on Infinium 450K DNA methylation

  • 1. Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway
  • 2. PharmaTox Strategic Research Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway
  • 3. Department of Pediatric and Adolescent medicine, Oslo University Hospital, Oslo, Norway
  • 4. Department of Pediatric Oncology and Hematology, Oslo University Hospital, Oslo. Norway

Description

DNA from ten subjects was isolated by three different extraction methods (MagNA Pure LC, Autopure LS, and manual organic extraction), and DNA methylation was analyzed using the Infinium HumanMethylation 450K Bead Chip.

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