Software Open Access
AN R PACKAGE FOR IDENTIFYING IMMUNE-RELATED SIGNALS IN TRANSCRIPTOME THROUGH DECONVOLUTION OR UNSUPERVISED SOURCE SEPARATION METHODS
You can install deconICA from GitHub with:
#install.packages("devtools") devtools::install_github("UrszulaCzerwinska/DeconICA", build_vignettes = TRUE, dependencies = TRUE)
The aim of the project is to adapt blind source separation techniques to extract immune-related signals from mixed biological samples. A great example of mixed biological sample is transcriptome measured in heterogenous tissue such as blood or tumor biopsy.