Journal article Open Access

Potential interventions for the prevention of childhood pneumonia: geographic and temporal differences in serotype and serogroup distribution of sterile site pneumococcal isolates from children—implications for vaccine strategies

Sniadack, David H.; Schwartz, Benjamin; Lipman, Harvey; Bogaerts, J.; Butler, Jay C.; Dagan, Ron; Echaniz-Aviles, Gabriela; Lloyd-Evans, Nellie; Fenoll, A.; Girgis, Nabil I.; Henrichsen, Jorgen; Klugman, Keith; Lehmann, Deborah; Takala, Aino K.; Vandepitte, J.; Gove, Sandy; Breiman, Robert F.

Streptococcus pneumoniae is a leading cause of fatal bacterial pneumonia in young children. Pneumococcal polysaccharide vaccines have not been promoted for use in young children because many constituent serotypes are not immunogenic in children

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