Journal article Open Access

A Review of Perineal Talc Exposure and Risk of Ovarian Cancer

Harlow, B. L.; Hartge, P. A.

The authors provide a detailed review of the events that led to the interest in talc as a possible ovarian carcinogen, the epidemiological studies published to date, and their perspective on the interpretation of the findings including potential limitations, biases, and issues surrounding the plausibility of a causal association. The authors conclude that the range of relative risk estimates from epidemiology, 1.0 to 1.8, is plausible, but that additional epidemiologic studies, especially prospective investigations are needed, In addition, clinicopathological studies are needed to confirm or deny the reports of talc embedded in human ovarian tissue and reports of talc migration through the human female reproductive tract.

Files (643.6 kB)
Name Size
article.pdf
md5:d2ccfc7f44342634458eb0bd9ff8767e
643.6 kB Download
32
28
views
downloads
Views 32
Downloads 28
Data volume 18.0 MB
Unique views 31
Unique downloads 28

Share

Cite as