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Published August 3, 2017 | Version v4
Dataset Open

The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling

Creators

  • 1. Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, University of California at San Francisco, San Francisco, CA 94158, USA.
  • 2. Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, University of California at San Francisco, San Francisco, CA 94158, USA.; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • 3. Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA.
  • 4. Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
  • 5. Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado, 80309, USA

Contributors

Data manager:

  • 1. University of California San Francisco

Description

This repository pertains to the molecular architecture of the yeast spindle pole body (SPB), the structural and functional equivalent of the metazoan centrosome. Data from in vivo FRET and yeast two-hybrid, along with SAXS, X-ray crystallography, and electron microscopy were integrated by a Bayesian structure modeling approach.

For more information about how to reproduce this modeling, see the Sali lab website or the README file.

Files

fret.zip

Files (7.6 GB)

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Additional details

Related works

Is supplement to
https://github.com/integrativemodeling/spb/tree/v1.0 (URL)
https://salilab.org/spb/ (URL)