Published November 29, 2023 | Version v1
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MORPHOMETRIC PARAMETERS OF THE ELEMENTS OF THE KNEE JOINT UNDER THE INFLUENCE OF EXPERIMENTAL HYPOTHYROIDISM

Description

Today, the number of patients with hypothyroidism among thyroid gland diseases is increasing. Decreased activity of the thyroid gland, more precisely, low concentration of thyroid hormone in the blood, leads to the derailment of metabolism in the body, and as a result, to some extent, the development of pathological changes. Its hypofunction originates and occurs due to several factors: gland injuries, tumor and cystic diseases, pituitary-hypothalamic system disorders, gland development defects, surgical intervention errors, long-term use of thyrostatic drugs, etc. Hypothyroidism is widespread among the population, iodine deficiency is one of the regional problems for our country.

This article describes the morphometric changes of the elements of the knee joint during early ontogeny in offspring born to mothers with experimental hypothyroidism during pregnancy. Experimental hypothyroidism model and research results allow early detection of morphofunctional changes of knee joint elements in offspring born from this disease and prediction of complications

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