Published September 27, 2025
| Version v1
Dataset
Open
An open CAR-T single-cell atlas to enable in-depth characterization and rational engineering of CAR-T products
Creators
-
Camara-Peña, Sergio
(Researcher)1, 2
-
Rodriguez-Marquez, Paula
(Researcher)1, 2, 3
-
Planell, Nuria
(Researcher)1, 2
-
Calleja-Cervantes, Maria E.
(Researcher)1, 2
-
Jordana-Urriza, Lorea
(Researcher)1, 2
-
Cinnirella, Giacomo
(Researcher)4
-
Reich-Zeliger, Shlomit
(Researcher)4
-
Rodriguez-Otero, Paula
(Researcher)2, 3, 5
-
Tamariz, Esteban
(Researcher)2, 5
-
Ochoa, Idoia
(Researcher)6
-
Yosef, Nir
(Researcher)4
-
Rodriguez-Madoz, Juan R.
(Researcher)1, 2, 3
-
Prosper, Felipe
(Researcher)1, 2, 3, 5
-
Hernaez, Mikel
(Researcher)1, 2, 3
-
1.
Fundación para la Investigación Médica Aplicada
-
2.
Navarre Institute of Health Research
-
3.
Centro de Investigación Biomédica en Red de Cáncer
-
4.
Weizmann Institute of Science
-
5.
Clinica Universidad de Navarra
-
6.
Universidad de Navarra
Description
This record contains the datasets used in the manuscript to ensure full reproducibility of the results.
- Code and analysis workflows are available at: https://github.com/ML4BM-Lab/Functional-cart-atlas
- Pretrained atlas model is broadly available to the community through scVI-hub: https://huggingface.co/sergiocamarap/Functional-cart-atlas-model
- Atlas is also accessible as an interactive Shiny application at: https://wholebioinfo.shinyapps.io/shinyatlas/
Together, these resources provide an integrated framework to explore, validate, and extend the CAR-T cell atlas presented in the study.
Files
Files
(23.0 GB)
| Name | Size | Download all |
|---|---|---|
|
md5:820f733164800bc1b9d04b84780c71c3
|
2.4 GB | Download |
|
md5:7ce93d47e62206156751bda3dcf5663c
|
5.1 GB | Download |
|
md5:0bf2ec99e8fa9be7f6e37be2d345399d
|
15.5 GB | Download |
Additional details
Software
- Repository URL
- https://github.com/ML4BM-Lab/Functional-cart-atlas
- Programming language
- Python, R
- Development Status
- Active