Published October 13, 2023 | Version v1
Dataset Open

Summary stats for Andrews, Kukkle, Menon et al. Indian Parkinson's Disease GWAS

  • 1. Denali Therapeutics
  • 2. MedGenome Labs

Description

GWAS summary stats for Andrews, Kukkle, Menon et al. "The genetic drivers of juvenile, young, and early-onset Parkinson's Disease in India"

Genomic coordinates in hg38. Results have been filtered for MAF > 0.05 and imputation quality (DR2) > 0.9. 

PDDiagnosis_GWAS.txt.gz - summary stats for PD diagnosis GWAS

CHR: chromosome

BP: base pair position

A1: effect allele

A2: alternative allele

BETA: odds ratio (with respect to A1)

SE: standard error

L95: confidence interval, lower bound

U95: confidence interval, upper bound

STAT: T-statistic

P: p-value

MAF: frequency of effect allele

MAF.cases: frequency of effect allele in cases (note: may exceed 0.5)

MAF.cont: frequency of effect allele in controls (note: may exceed 0.5)

DR2: Beagle imputation quality metric

 

AgeofOnset_GWAS.txt.gz - summary stats for age of onset GWAS

CHR: chromosome

BP: base pair position

A1: effect allele

A2: alternative allele

BETA: regression coefficient (with respect to A1)

SE: standard error

L95: confidence interval, lower bound

U95: confidence interval, upper bound

STAT: T-statistic

P: p-value

MAF: frequency of effect allele

DR2: Beagle imputation quality metric

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