Ultrasound Shear Wave Elastography in the Evaluation of Liver Fibrosis

Background: Chronic hepatitis B virus (HBV) infection affects about 296 million people worldwide and is the leading etiology of cirrhosis and liver cancer globally. In China, chronic hepatitis B has grown to be a significant public health issue. NAFLD (non-alcoholic fatty liver disease) is one of the primary causes of cirrhosis in the globe. Up to 10.3% of NAFLD patients, according to the National Health and Nutrition Examination Survey, had advanced fibrosis. These findings suggest that the real-time Shear wave elastography (SWE) can be used for the assessment of significant fibrosis, sever fibrosis and Cirrhosis. Objective: To determine the ultrasound shear wave elastography in the evaluation of liver fibrosis. Methods: A cross-sectional study was conducted at First affiliated hospital of Xinjiang Medical university, which was performed between January 2020 and March 2023. The total patients in our study was 118. In 118 consecutive patients who underwent Ultrasound Shear wave elastography (SWE) before their scheduled liver biopsy (59 men, 59 women). We used Michael Mindray ultrasound machine and its frequency was C6-1. The stages of liver fibrosis according to the METAVIR classification system. Results: F2 stage of fibrosis is more as compare as compare to others. Liver fibrosis is more common in females as comapre to males. According to the age males have higher risk as compare to females. Total patients in our study was 118. Mean age for males patienst were 44.8983 and for females 48.9492. MEAN±SD of Alanine aminotransferase (ALT) was 92.6±116.14 u/L. The frequency of patients with F0 was 33 (28.0 %), F1 was 5 (4.2%), F2 was 58 (49.2%), F3 was 9 (7.6%) F4 was 13 (11.0%). Frequency of no fatty liver was 49, mild fatty liver was 39, moderate fatty liver was 8, sever fatty liver was 22. Hepatitis B was present in 96 patients and was not present in 22 patients out of 118. Hepatitis C was present in 116 patients and was not present in 2 patients out of 118 (1.7). P-value of hepatitis B is 0.34. P-value of hepatitis C is 1.0. P-value of stages of Liver fibrosis with respect to gender is 0.005. Conclusion: Our result concluded that fibrosis stage F2 patients are more in our study (Heaptitis B). Liver fibrosis is more common in females as comapre to males. According to the age males have higher risk as compare to females. Shear wave elastography (SWE) is a straightforward, quick, and repeatable technique for noninvasively assessing liver fibrosis. Benefits include its low cost and global availability.