ProteinCartography v0.4 analyses for sample of most-studied human proteins
Description
Results from running the ProteinCartography pipeline (v0.4) using analyses on 25 proteins sampled from the most-studied human proteins listed in Liu and Buck, 2021.
The proteins included are listed in the table below. The results for each analysis are provided as individually-zipped folders, with the name of the file reflective of the protein name. To download all of the analyses in one folder, you can download the "25humanprotein_analysis.zip" file.
UniProt ID |
Protein name |
Protein symbol (in figures) |
Q9UM73 |
ALK tyrosine kinase receptor |
ALK |
Q96RI1 |
Bile acid receptor |
NR1H4 |
P43235 |
Cathepsin K |
CATK |
P08603 |
Complement factor H |
CFAH |
P00374 |
Dihydrofolate reductase |
DYR |
P98170 |
E3 ubiquitin-protein ligase XIAP |
XIAP |
P49841 |
Glycogen synthase kinase-3 beta |
GSK3B |
P01112 |
GTPase HRas |
RASH |
P68871 |
Hemoglobin subunit beta |
HBB |
P04439 |
HLA class I histocompatibility antigen, A alpha chain |
HLAA |
P01834 |
Immunoglobulin kappa constant |
IGKC |
P14174 |
Macrophage migration inhibitory factor |
MIF |
P53779 |
Mitogen-activated protein kinase 10 |
MK10 |
Q15596 |
Nuclear receptor coactivator 2 |
NCOA2 |
Q99497 |
Parkinson disease protein 7 |
PARK7 |
P62937 |
Peptidyl-prolyl cis-trans isomerase A |
PPIA |
Q13451 |
Peptidyl-prolyl cis-trans isomerase FKBP5 |
FKBP5 |
P27986 |
Phosphatidylinositol 3-kinase regulatory subunit alpha |
P85A |
O75530 |
Polycomb protein EED |
EED |
P28074 |
Proteasome subunit beta type-5 |
PSB5 |
P19793 |
Retinoic acid receptor RXR-alpha |
RXRA |
P50120 |
Retinol-binding protein 2 |
RET2 |
P00441 |
Superoxide dismutase [Ccu-Zn] |
SODC |
Q93009 |
Ubiquitin carboxyl-terminal hydrolase 7 |
UPB7 |
P40337 |
von Hippel -–Lindau disease tumor suppressor |
VHL |
A TSV file, "most_studied_human_proteins.tsv", is included for use with the analysis notebook ("pub/most_studied_human_proteins.ipynb") found in our GitHub repository for the Arcadia Science Pub "ProteinCartography: Comparing proteins with structure-based maps for interactive exploration". The notebook produces the outputs, "sampled_proteins.tsv", and. "most_studied_human_proteins_analysis.tsv", which are used by the analysis notebook ("pub/cluster_quality_human_proteins.ipynb"), which uses the contents of this deposition.
Files
25humanprotein_analysis.zip
Files
(15.6 GB)
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