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Published 2024 | Version v2
Dataset Open

TLNRD1 is a CCM complex component and regulates endothelial barrier integrity

  • 1. School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK
  • 2. Faculty of Science and Engineering, Cell Biology, Åbo Akademi, University, 20520 Turku, Finland
  • 3. Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520, Turku, Finland

Description

Raw microscopy images used to make the figures displayed in the article "TLNRD1 is a CCM complex component and regulates endothelial barrier integrity."

https://www.biorxiv.org/content/10.1101/2023.09.29.559344v1

Notes

This study was supported by the Research Council of Finland (338537 to G.J.; 325464 to J.I.; and 332402 to G.F.), the Sigrid Juselius Foundation (to G.J. and to J.I.), the Cancer Society of Finland (Syöpäjärjestöt; to G.J. and to J.I.), and the Solutions for Health strategic funding to Åbo Akademi University (to G.J.). This research was supported by the InFLAMES Flagship Programme of the Academy of Finland (decision numbers: 337530, 337531, 357910, and 357911). This work was also supported by the Finnish Cancer Institute (K. Albin Johansson Professorship, J.I.), the Centre of Excellence program (# 346131, J.I.), and the Jane and Aatos Erkko Foundation (J.I.). B.T.G. was supported by the Biotechnology and Biological Sciences Research Council grant (BB/S007245/1) and the Cancer Research UK Program Grant (CRUK-A21671). The Cell Imaging and Cytometry Core facility, the Zebrafish Core (both at Turku Bioscience, University of Turku, Åbo Akademi University, and supported by Biocenter Finland), Turku Bioimaging and the Genome Biology Unit (Research Programs Unit, HiLIFE Helsinki Institute of Life Science, Faculty of Medicine, University of Helsinki, Biocenter Finland) are acknowledged for services, instrumentation, and expertise. Mass spectrometry was performed at the Turku Proteomics Facility, University of Turku and Åbo Akademi University. The facility is supported by Biocenter Finland.

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Additional details

Related works

Is referenced by
Preprint: 10.1101/2023.09.29.559344 (DOI)

Funding

Filopodia-mediated communication in cancer progression (FILOCOM) 338537
Research Council of Finland
Adhesion dynamics and mechanobiological pathways as determinants of oncogenic properties 325464
Research Council of Finland
Harnessing protein unfolding and aggregation in mechanotransduction BB/S007245/1
UK Research and Innovation
Deciphering the mechanisms of pancreatic cancer metastasis (PanCanMet) 332402
Research Council of Finland
InFLAMES: Innovation Ecosystem based on the Immune System / Consortium: InFlames 337531
Research Council of Finland