Published September 26, 2023 | Version 1.0

Testing of Medtronic Percept PC with MEG phantom

  • 1. Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, London, UK
  • 2. Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany
  • 3. Medtronic Bakken Research Center, Maastricht, The Netherlands

Description

The combination of subcortical Local Field Potential (LFP) recordings and stimulation with Magnetoencephalography (MEG) in Deep Brain Stimulation (DBS) patients enables the investigation of cortico-subcortical communication patterns and provides insights into DBS mechanisms. Until now, these recordings have been carried out in post-surgical patients with externalised leads. However, a new generation of telemetric stimulators makes it possible to record and stream LFP data in chronically implanted patients. Nevertheless, whether such streaming can be combined with MEG has not been tested.

In the present study, we tested the most commonly implanted telemetric stimulator – Medtronic Percept PC with a phantom in three different MEG systems: two cryogenic scanners (CTF and MEGIN) and an experimental Optically Pumped Magnetometry (OPM)-based system.

The dataset and code herein make it possible to reproduce most of the figures in the paper and examine additional conditions not described in detail in the paper. The data can be useful for developing, testing and benchmarking MEG artefact removal methods.

Files

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Additional details

Related works

Is supplement to
Preprint: 10.1101/2023.07.17.549294 (DOI)
Journal article: 10.1162/imag_a_00029 (DOI)
Is supplemented by
Software: https://github.com/vlitvak/meg-phantom-perceptPC (URL)

Funding

Wellcome Trust
Wellcome Centre for Human Neuroimaging 203147