Published September 22, 2022
| Version v2
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Integrated transcriptomic landscape of the effect of anti-steatotic treatments in high fat diet mouse models of non-alcoholic fatty liver disease
Creators
- 1. Departamento de Farmacología, Universitat de València, Valencia, Spain & FISABIO (Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana), Valencia, Spain
- 2. Bioinformatics and Biostatistics Unit, Principe Felipe Research Center, Valencia, Spain
- 3. Bioinformatics and Biostatistics Unit, Principe Felipe Research Center, Valencia, Spain & Facultad de Ciencias de la Salud. Universidad San Jorge, Zaragoza, Spain
- 4. Departamento de Farmacología, Universitat de València, Valencia, Spain; FISABIO (Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana), Valencia, Spain & CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Spain
- 5. FISABIO (Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana), Valencia, Spain; CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Spain & Departamento de Fisiología, Universitat de València, Valencia, Spain
Description
Results and supplementary material of the manuscript "Integrative and comparative study of the effect of anti-steatotic treatments on the transcriptome in high fat diet mouse models of NAFLD using a meta-analysis".
The content of the files is detailed below:
- 00_R_package_versions.xlsx. Version of R and of the packages used in the analyses.
- Results of the 3 differential gene expression (DGE) comparisons. Each sheet corresponds to the results of one of the individual studies analyzed.
- 01-DGE_HFD-vs-ND.xlsx
- 01-DGE_HFDt-vs-HFD.xlsx
- 01-DGE_HFDt-vs-ND.xlsx
- 02_DGE_Meta-analyses_results.xlsx. Results of the 3 DGE meta-analyses performed (one per comparison). The results of each meta-analysis are in a different tab.
- Results of the 3 differential gene expression (GSA) comparisons. Each sheet corresponds to the results of one of the individual studies analyzed.
- 03-GSA_HFD-vs-ND.xlsx
- 03-GSA_HFDt-vs-HFD.xlsx
- 03-GSA_HFDt-vs-ND.xlsx
- 04_GSA_Meta-analyses_results.xlsx. Results of the 3 GSA meta-analyses performed (one per comparison). The results of each meta-analysis are in a different tab.
- 05_Phenotipic data about treatments' effects.xlsx. Available data on the metabolic and hepatic changes induced by each of the anti-steatotic treatment studied in the meta-analysis.
- 06_Phenotipic data about HFD models.xlsx. Available data on the metabolic and hepatic changes induced by the different high fat diet mouse models employed in the meta-analysis.
The first tab of each file contains an explanation of the abbreviations.
Significant results of the work and the exploratory analysis of the individual GEO studies are also available in the web tool: http://bioinfo.cipf.es/metafun-HFD/
Files
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