Significance of laboratory markers in covid-19 associated myocarditis in pregnant women

Abstract. Purpose: to assess the level of laboratory markers (troponin I and NT-proBNP) in pregnant women with COVID-19 associated myocarditis and their correlation with the severity of the disease. Methods. Based on the selection results, a group of 46 pregnant women was identified who were diagnosed with COVID-19 associated myocarditis based on the results of a comprehensive clinical, instrumental and laboratory study. During the study, all pregnant women underwent laboratory assessment of the level of troponin I (cTnI) and N-terminal B-type natriuretic peptide (NT-proBNP) in the blood. Results. An increase in cTnI was noted in 100% of cases. At the same time, the average value in the group was 12.4±6.3 ng/ml, which exceeds the reference value by 30 times. An increase in NT-proBNP was also noted in 100% of cases. The average value in the sample was 146.2±32.6 pg/ml. It should be noted that in most cases there was an increase in NT-proBNP >128 pg/ml. Conclusion. NT-proBNP in the blood is not only an indirect indicator of the presence of this pathology, but also a criterion for the severity of the condition, as well as a predictor of the development of severe complications in the cardiovascular system over time.