Published September 4, 2023
| Version 1
Dataset
Open
Analysis of AaH-II effect in the axon initial of neocortical pyramidal neurons
Description
This dataset contains data in HEK293 neurons expressing either human Nav1.2 or human Nav1.6 and whole-cell electrophysiological recordings and imaging data from neocortical layer-5 pyramidal neuron in brain slices of the mouse.
This dataset is used in the paper:
Abbas F, Blömer LA, Millet H, Montnach J, De Waard M, Canepari M. Analysis of the effect of the scorpion toxin AaH-II on action potential generation in the axon initial segment. bioRxiv, 2023. https://www.biorxiv.org/content/10.1101/2023.10.06.561226v1
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Additional details
Funding
- Nav12RESCUE – Rescue of Nav1.2 Sodium Channel Functions in Severe Neurodevelopmental Disorders ANR-21-CE18-0042
- Agence Nationale de la Recherche
- ICST – Canaux ioniques d'intérêt thérapeutique ANR-11-LABX-0015
- Agence Nationale de la Recherche