Published December 1, 2012 | Version v1
Journal article Open

The Evaluation of Effect of Phototherapy on Serum Calcium Level

  • 1. Department of Paediatrics, M.L.B. Medical College, Jhansi - 284128 (Uttar Pradesh)

Description

Jaundice is one of the most common problem that can occur in the newborn. The study group included 30 neonates (15 term and 15 preterm) and control group included 20 neonates (10 terms & 10 preterm). All had hyperbilirubinemia. The controls were fully matched with the study group. All the neonates included in the study group required management with phototherapy. The neonates in the control group were managed without phototherapy. Measurement of ionized serum calcium level was done before and after 48 hours of institution of phototherapy in study groups and controls. Before phototherapy, there was no statistical significant difference in mean serum calcium level in term & preterm neonates of both study & control group. After 48 hours of phototherapy in study group, a significant fall in calcium level in 66.6% of term & 80% of preterm neonates was observed. Whereas, no difference was observed in control group. It is suggested that calcium level be assessed in neonates treated with phototherapy for more then 48 hours and managed accordingly.

Files

1. Rajesh Kumar .pdf

Files (27.1 kB)

Name Size Download all
md5:c8eed1c4b6b54ee2dcac6f40275fbcae
27.1 kB Preview Download

Additional details

References

  • 1. American Academy of Pediatrics. Practice parametermanagement of hyperbilirubinemia in healthy term and preterm newborn. Pediatric, 1994;94:555-565
  • 2. Bergman L: Plasma calcium fractions during the first days of life with special reference to neonatal hypocalcaemia. Biology of the Neonates, 1972; 20(5- 6): 346-359.
  • 3. Cashore WJ: Bilirubrin and Joundice in micropremie. Clinics in Perinatology, 2000;27(1):171-179.
  • 4. Gutcher GR, Odell GB: Hypocalcaemia associated with phototherapy in newborn rats: Light source dependence. Photochemistry & Photobiology, 1983;37(2): 177-180.
  • 5. Hakanson DO, Bergstrom WH: Phototherapy induced hypocalcemia in newborn rats. Prevention by Melatonin. Science, 1981;214(4522):807-809.
  • 6. Hunter KM: Hypocalcaemia. In: Manual of Neonatal Care. JP Cloherty, EC Eichenwald, AR Stark (Eds.); 5th Edn.; Lippincott Williams & Wilkins, Philadelphia. 2004;pp.579-588
  • 7. Jain, BK, Singh H, Singh D, Toor NS.: Phototherapy induced hypocalcemia. Indian Pediatrics, 1998;35(6):566-567
  • 8. Medhat FB: Assessment of phototherapy induced hypocalcaemia. Thesis submitted for M.Sc. Pediatrics in Cairo University. Classification no. 8461; 2006.
  • 9. Meherban S: Jaundice. In: Care of newborns. 6th Edn.; Sagar Publication, New Delhi. 2004;pp. 239-255.
  • 10. Romagnoli C, Polidori G, Cataldi L, Tortorlo SG, Segni G: Phototherapy induced hypocalcaemia. The Journal of Pediatrics, 1979; 94(5):813-816.
  • 11. Sethi H, Saili A, Dutta AK: Phototherapy induced hypocalcaemia. Indian Pediatrics, 1993; 30(12):1403- 1406.
  • 12. Tan KL: Phototherapy for neonatal jaundice. Clinics in Perinatology, 1991;18(3):423-439.