Published June 29, 2023 | Version v1
Dataset Open

Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration

Description

Mice lacking Rab27b show enhanced retinal ganglion cell axon regeneration after optic nerve crush and greater motor function and raphespinal sprouting after spinal cord trauma. Thus, a comprehensive functional screen reveals multiple pathways restricting axonal regeneration and neurological recovery after injury.

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