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Published June 20, 2023 | Version V2
Dataset Open

The Mexican dataset of an rTMS clinical trial on cocaine use disorder patients: SUDMEX TMS

  • 1. Instituto de Neurobiología, Universidad Nacional Autónoma de México campus Juriquilla, Querétaro, Mexico.
  • 2. 5 Interdisciplinary Institute for Neuroscience, University 0000-0003-4757-9040of Bordeaux, Bordeaux, France.
  • 3. Faculty of Psychology, Universidad Anáhuac México Sur, Mexico City, Mexico.
  • 4. Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñız, Mexico City, Mexico.

Description

The SUDMEX_TMS dataset is the result of a longitudinal clinical trial of cocaine use disorder patients that were treated with rTMS at 5-Hz on the left dorsolateral prefrontal cortex (lDLPFC) for a 2 week double-blind acute phase and an open-label maintenance phase that included clinical, cognitive and MRI data acquisition. The design was a double-blind placebo-controlled randomized controlled trial with parallel groups (acute phase). The study was done at the National Institute of Psychiatry .

Each patient had more than one clinical and MRI session or time point from baseline (T0), 2 weeks (T1), 3 months (T2), 6 months (T3) and some patients had 12 months (T4). The T14 time point was only for patients in the Sham group who decided to continue the clinical trial with open-label rTMS. The T14 refers to 2 weeks after T1 (4 weeks after T0).

The MRI sequences were: 1) T1-weighted, 2) rsfMRI 10 min, 3) HARDI-DWI multishell (next release).

 

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