Published June 7, 2023 | Version v1
Dataset Open

PubChem lists to Study the Exposome of Mild Cognitive Impairment and Alzheimer's Disease on Cerebrospinal Fluid

Description

Collection of 4 lists of chemicals associated to Alzheimer's disease (AD) and related disorders. 

The following table describes the mentioned lists. 

Name Description
AD-database Database of 41,917 chemicals related to AD and other neurodegenerative disorders.  CIDs co-ocurring with the 27 selected MeSH terms (*see below) were merged and mapped to the parent CIDS.
TOP1 List of 1,268 chemicals having D000544 (AD MeSH code) as the first neighbor .
SC20 List of 247 chemicals created after truncating by 1/20 of the maximum co-ocurrence score of the chemical neighbors for D000544. 
AD-CTD List of 86 chemicals specifically related to AD in the Comparative Toxicogenomic Database (CTD)

 *Selected MeSH terms for the AD-database: D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647,D000647 and D000647.

HMDB-CSF can be downloaded here.

PubChemLite for Exposomics (version 1.12.0) can be found here.

Files

AD-CTD.csv

Files (19.9 MB)

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md5:1e4106c063bb2cf07a4a0640667d96e7
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md5:95e0c6975e4454acde99be9aaa8b725e
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md5:8c8bc12989264949cbf9b84e87d6d227
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md5:e41460d45f7d8b19341232066f7f34d7
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Additional details

Related works

Cites
https://github.com/rickhelmus/patRoon (URL)
Is identical to
Presentation: 10.5281/zenodo.8012871 (DOI)
Is referenced by
Presentation: 10.5281/zenodo.8014269 (DOI)