Published October 6, 2022 | Version v2
Journal article Open

Opto-RhoGEFs: an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength

  • 1. Swammerdam Institute for Life Sciences, Section of Molecular Cytology, van Leeuwenhoek Centre for Advanced Microscopy, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands
  • 2. Molecular Cell Biology Lab at Dept. Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands

Description

These are the datasets that are related to the manuscript 'Opto-RhoGEFs: an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength' by

Eike K. Mahlandt1, Sebastián Palacios Martínez1, Janine J. G. Arts1,2, Simon Tol2, Jaap D. van Buul1,2, Joachim Goedhart1*

 

1 Swammerdam Institute for Life Sciences, Section of Molecular Cytology, van Leeuwenhoek Centre for Advanced Microscopy, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam,

The Netherlands

2 Molecular Cell Biology Lab at Dept. Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands

* Correspondence:

Email: j.goedhart@uva.nl | Twitter: @joachimgoedhart | ORCID: 0000-0002-0630-3825

 

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