Formulation and Evaluation of Poly Herbal Chewable Tablets from Ayurvedic Ingredients having Cough Relieving Activity

In recent years, there is a spurt in the interest
regarding use of Ayurvedic forms of medication.
Glycyrrhiza Glabra (Liquorice), Zingiber Officinale
(Ginger), Curcuma longa (Turmeric) has been used as
medicine from ancient times for treating the cough.
These herbal drugs use was mentioned in Ayurveda.
Cough affects patients of every age, so it is the common
disease condition. Because of better patient compliance,
flexible design of dosage forms, ease of administration
and least sterility requirements, oral route of drug
administration is the well liked route. The goal of this
research work is to develop Polyherbal chewable tablets
of various Ayurvedic Drugs by wet granulation method
and to evaluate the formulations for various
pharmaceutical parameters. The purpose of this study
was to produce polyherbal chewable tablets using
Liquorice, Ginger, Turmeric. These polyherbal
chewable tablets were formulated by technique of wet
granulation method by utilizing binder that is acacia
gum (5% w/v). Quality of final polyherbal chewable
tablet was evaluated for pre formulation and post
formulation parameter. Bulk and tapped densities, angle
of repose, Carr's index, and Hausner's ratio are the preformulation tests evaluated for the prepared powder
mixture (blend). Polyherbal chewable tablets were
examined for general appearance, tablet size and shape,
hardness, friability, weight variation as well as duration
of disintegration.