Published March 21, 2023 | Version v2
Journal article Open

Suplementación con β-hidroxi-β- metil butirato en el envejecimiento

Authors/Creators

  • 1. Medicina Interna. Hospital Universitario General de Villalba. Madrid

Description

Existen numerosas revisiones sistemáticas que valoran la efectividad de la suplementación con β-hidroxi-β-metil butirato (HMB) para reducir la sarcopenia en personas mayores y, en la práctica clínica, para atenuar la perdida de músculo y promover la ganancia del mismo. El objetivo de esta revisión es repasar estas revisiones sistemáticas.

 

There are numerous systematic reviews of HMB and its effectiveness in older persons in mitigating sarcopenia and in clinical practice to attenuate muscle loss or promote muscle gain. The main aim of this review was to conduct an umbrella review of these systematic reviews in which HMB was examined for its effects on older persons and clinical populations.

Files

Journal 59 - 03.pdf

Files (504.5 kB)

Name Size Download all
md5:723fd1b9c45c64fa59febe619e78f763
504.5 kB Preview Download

Additional details

References

  • Vol. 7. N 10. 2007. Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. Doi: https://doi.org/10.1186/1471-2288-7-10
  • Vol. 79. N 2. Págs. 121-147. 2021. Gielen E, Beckwée D, Delaere A, De Breucker S, Vandewoude M, Bautmans I. Nutritional interventions to improve muscle mass, muscle strength, and physical performance in older people: an umbrella review of systematic reviews and meta-analyses. Nutr Rev. Doi: https://doi.org/10.1093/nutrit/nuaa011
  • Vol. 33. N 1. págs. 71-82. 2009. Baier S, Johannsen D, Abumrad N, Rathmacher JA, Nissen S, Flakoll P. Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-beta-methylbutyrate (HMB), L-arginine, and L-lysine. JPEN J Parenter Enteral Nutr. Doi: https://doi.org/10.1177/0148607108322403
  • Vol. 20. N 5. págs. 445-451. 2004. Flakoll P, Sharp R, Baier S, Levenhagen D, Carr C, Nissen S. Effect of beta-hydroxy-beta-methylbutyrate, arginine, and lysine supplementation on strength, functionality, body composition, and protein metabolism in elderly women. Nutrition. Doi: https://doi.org/10.1016/j.nut.2004.01.009
  • Vol. 35. N 1. págs. 18-26. 2016. Deutz NE, Matheson EM, Matarese LE, Luo M, Baggs GE, Nelson JL, et al. Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial. Clinical Nutrition. Doi: https://doi.org/10.1016/j.clnu.2015.12.010
  • Vol. 32 N 5. págs. 704-712. 2013. Deutz NE, Pereira SL, Hays NP, Oliver JS, Edens NK, Evans CM, et al. Effect of beta-hydroxy-beta-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults. Clinical Nutrition. Doi: https://doi.org/10.1016/j.clnu.2013.02.011