Published March 22, 2023
| Version 1
Journal article
Open
4-year survival and biomarkers evaluation from a phase II study of sequential immunotherapy and targeted therapy for metastatic BRAF V600-mutated melanoma (SECOMBIT)
Authors/Creators
- Paolo Antonio Ascierto1
- Milena Casula2
- Jenny Bulgarelli3
- Marina Pisano2
- Claudia Piccinini3
- Luisa Piccin4
- Antonio Cossu5
- Mario Mandalà6
- Pier Francesco Ferrucci7
- Piotr Rutkowski8
- Virginia Ferraresi9
- Ana Arance10
- Michele Guida11
- Evaristo Maiello12
- Helen Gogas13
- Erika Richtig14
- Maria Teresa Fierro15
- Celeste Lebbe16
- Hildur Helgadottir17
- Paola Queirolo18
- Francesco Spagnolo18
- Marco Tucci19
- Michele Del Vecchio20
- Maria Gonzales Cao21
- Alessandro Marco Minisini22
- Sabino De Placido23
- Miguel F Sanmamed24
- Domenico Mallardo1
- Miriam Paone1
- Maria Grazia Vitale1
- Ignacio Melero24
- Antonio M Grimaldi25
- Diana Giannarelli26
- Reinhard Dummer27
- Vanna Chiarion Sileni4
- Giuseppe Palmieri2
- 1. Department of Melanoma, Cancer Immunotherapy and Development Therapeutics. I.N.T. IRCCS Fondazione "G. Pascale" Napoli
- 2. Immuno-Oncology & Targeted Cancer Biotherapies, University of Sassari - Unit of Cancer Genetics, IRGB-CNR, 07100 Sassari, Italy
- 3. Immunotherapy, Cell Therapy Unit and Biobank Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy
- 4. Melanoma Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy
- 5. Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy
- 6. 6 University of Perugia, Perugia, Italy
- 7. Biotherapy of Tumors Unit, Department of Experimental Oncology, European Institute of Oncology, IRCCS, Milan, Italy
- 8. Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska Curie National Research Institute of Oncology, 02-781 - Warsaw/PL
- 9. Department of Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome, Italy
- 10. Department of Medical Oncology, Hospital Clínic Barcelona, 08036 - Barcelona/ES
- 11. Rare tumors and Melanoma Unit, IRCCS Istituto dei Tumori "Giovanni Paolo II", Bari, Italy
- 12. Oncology Unit, Foundation IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
- 13. First Department of Medicine, National and Kapodistrian University of Athens, Greece
- 14. Department of Dermatology, Medical University of Graz, Graz, Austria
- 15. Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy
- 16. Université Paris Cite, Dermato-Oncology and CIC AP-HP Hôpital Saint Louis,Cancer Institute APHP.Nord-Université Paris Cite F-75010 Paris, France; INSERM U976
- 17. Department of Oncology-Pathology, Karolinska Institutet and Karolinska University Hospital Solna, Stockholm, Sweden
- 18. IRCCS Ospedale Policlinico San Martino, Skin Cancer Unit, Genova, Italy
- 19. Department of Interdisciplinary Medicine, Oncology Unit, University of Bari "Aldo Moro", Bari, Italy
- 20. Unit of Melanoma Medical Oncology, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan
- 21. Department of Medical Oncology, University Hospital Dexeus, Barcelona, Spain
- 22. Academic Hospital "Santa Maria della Misericordia", Udine, Italy
- 23. Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy
- 24. Department of Immunology and Oncology, Clínica Universidad de Navarra, Pamplona, Spain
- 25. Medical Oncology Unit, AORN San Pio Benevento
- 26. Fondazione Policlinico Universitario A. Gemelli, IRCCS – Facility of Epidemiology and Biostatistics, Rome
- 27. Department of Dermatology, University and University Hospital Zurich, Zurich, Switzerland
Description
4-year survival data of clinical trial SECOMBIT
Files
protocol_21.02961_cover-page.pdf
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(178.5 MB)
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