Published July 24, 2021 | Version v1
Poster Open

Optofluidic Force Induction Scheme for the Characterization of Nanoparticle Ensembles

  • 1. Institute of Physics, University of Graz; Brave Analytics GmbH
  • 2. Brave Analytics GmbH
  • 3. Institute of Biophysics, Medical University of Graz
  • 4. Brave Analytics GmbH; Institute of Biophysics, Medical University of Graz
  • 5. Institute of Physics, University of Graz


Momentum transfer from light to matter provides the basic principle of optical tweezers. Most studies have hitherto employed this principle for trapping and manipulation of single nanoparticles. However, in a microfluidic channel one can also monitor the effect of optical forces exerted on ensembles of dielectric nanoparticles, to acquire knowledge about various nanoparticle parameters, such as size, shape or material distributions.

Here, we present an optofluidic force induction scheme (OF2i) for real-time, on-line optical characterization of nanoparticles. Our experimental setup builds on precisely controlled fluidics as well as optical elements, in combination with a focused laser beam with orbital angular momentum. By monitoring the single particle light scattering and trajectories in presence of optical and fluidic forces, we obtain detailed information about the properties of the individually tracked particles.

We analyse the trajectories using a detailed simulation approach based on Maxwell’s equations and Mie’s theory, in combination with laser fields and fluidic forces. We discuss the basic physical principles underlying the OF2i scheme and demonstrate its applicability. Our results prove that OF2i provides a flexible work bench for numerous applications.



Files (1.6 MB)

Name Size Download all
1.6 MB Preview Download

Additional details


NanoPAT – Process Analytical Technologies for Industrial Nanoparticle Production 862583
European Commission