Published March 7, 2023 | Version v1
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"EQUINE ASTHMA" SYNDROME – CLINICAL, ENDOSCOPIC AND BACTERIOLOGIC INVESTIGATIONS IN EIGHT TINKER HORSES

Authors/Creators

  • 1. Trakia University, Faculty of Veterinary Medicine, Stara Zagora, Bulgaria

Contributors

  • 1. University of Forestry

Description

The present study included 8 mares of the Tinker breed with clinic of Recurrent airway obstruction (RAO), characterized by difficulty breathing, coughing, rapid fatigue during exercise. No changes in body temperature and heart rate were found. There were no abnormalities in erythrocyte count, erythrocyte indices, hemoglobin, hematocrit, platelets, leukocytes and differential blood count. Tracheal endoscopy revealed an accumulation of increased mucus (grade 3–5), edema of the tracheal bifurcation, and spasm of the main bronchi. The following microorganisms were isolated in tracheal lavage (TW): Streptococcus equi, subsp. zooepidemicus (2 horses), Streptococcus pneumoniae (1 horse), Pasteurella spp. (1 horse), Klebsiella pneumoniae (1 horse) and Pseudomonas aeruginosa (1 horse). Cytological examination of tracheal specimens revealed mainly neutrophil leukocytes. The other cells observed (macrophages and lymphocytes) were in a significantly lower percentage.

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References

  • Bond S.L., Timsit E., Workentine M., Alexander T., Léguillette R. (2017). Upper and lower respir-atory tract microbiota in horses: bacterial communities associated with health and mild asthma (inflammatory airway disease) and effects of dexamethasone. BMC Microbiology, 17, 184.
  • Bullone M., Lavoie J.P. (2015). Asthma "of horses and men" – how can equine heaves help us better understand human asthma immunopathology and its functional consequences? Mol Immunol, 66, 97–105.
  • Cardwell J.M., Smith K.C., Wood J.L.N., Newton J.R. (2014). Infectious risk factors and clinical indicators for tracheal mucus in British National Hunt racehorses. Equine Vet J, 46, 150-155.
  • Cardwell J.M., Wood J.L.N., Smith K.C., Newton J.R. (2011). Descriptive results from a longitudi-nal study of airway inflammation in British National Hunt racehorses. Equine Vet J, 43, 750–755.
  • Couëtil L., Hawkins J. (2013). Diagnostic tests and therapeutic procedures. In: Couëtil L, Hawkins J, editors. Respiratory Diseases of the Horse. London: Manson Publishing Ltd, 55–58
  • Couëtil L.L., Cardwell J.M., Gerber V., Lavoie J.P., Léguillette R., Richard E.A. (2016). Inflammatory airway disease of horses – revised consensus statement. J Vet Intern Med, 30, 503–515.
  • Couetil L.L., Hoffman A.M., Hodgson. J. (2007). Inflammatory airway disease of horses. J Vet Intern Med, 21, 356–361.
  • Couetil L.L., Rosenthal F.S., DeNicola D.B., Chilcoat C.D.(1985). Clinical signs, evaluation of bronchoalveolar lavage fluid, and assessment of pulmonary function in horses with inflammatory respiratory disease. Am J Vet Res, 62, 538–546.
  • Couetil L.L., Ward M.P. (2003). Analysis of risk factors for recurrent airway obstruction in North American horses: 1,444 cases (1990–1999). J Am Vet Med Assoc, 223, 1645–1650.
  • Derksen F.J., Scott J.S., Miller D.C. (1985). Bronchoalveolar lavage in ponies with recurrent airway obstruction (heaves). Am Rev Respir Dis, 132, 1066–1070.
  • Feudo C.M., Stucchi L., Alberti E., Stancari G., Conturba B., Zucca E., Ferrucci F. (2021). The role of thoracic ultrasonography and airway endoscopy in the diagnosis of equine asthma and exercise-induced pulmonary hemorrhage. Vet Sci, 15, 8 (11), 276.
  • Gerber V., Lindberg A., Berney C., Robinson N.E. (2004). Airway mucus in recurrent airway obstruction–short-term response to environmental challenge. J Vet Intern Med, 18, 92–97.v
  • Hoffman A.M. (2008). Bronchoalveolar lavage: sampling technique and guidelines for cytologic preparation and interpretation. Vet Clin North Am Equine Pract, 24, 423–435.
  • Holcombe S.J., Robinson N.E., Derksen F.J. (2006). Effect of tracheal mucus and tracheal cytology on racing performance in Thoroughbred racehorses. Equine Vet J, 38, 300–304.
  • Hotchkiss J.W., Reid S.W.J., Christley R.M. (2007). A survey of horse owners in Great Britain regarding horses in their care. Part 2: risk factors for recurrent airway obstruction. Equine Vet J, 39, 301–308.
  • Houtsma A., Bedenice D., Pusterla N., Pugliese B., Mapes S., Hoffman A.M., Rozanski J.P., Mukherjee J., Wigley M., Mazan M.R. (2015). Association between inflammatory airway disease of horses and exposure to respiratory viruses: a case control study. Multidisciplinary Respiratory Medicine, 10, 33.
  • Koblinger K., Nicol J., McDonald K. (2011). Endoscopic assessment of airway inflammation in horses. J Vet Intern Med, 25, 1118–1126.
  • Laus F., Attili A.R., Cerquetella M., Spaterna A., Tesei B., Cuteri V. (2009). Endoscopic findings, microbiological and cytological evaluation of tracheal aspirates in a population of Standardbred horses with poor performances. Veterinarni Medicina, 54, 444–450.
  • Leclere M., Lavoie-Lamoureux A., Lavoie J. (2011). Heaves, an asthma-like disease of horses. Respirology, 16, 1027–1046.
  • Mair T.S., Stokes C.R., Bourne F.J. (1987). Cellular content of secretions obtained by lavage from different levels of the equine respiratory tract. Equine Vet J, 19, 458–462.
  • Malikides N., Hughes K.J., Hodgson D.R., Hodgson J.L. (2003). Comparison of tracheal aspirates and bronchoalveolar lavage in racehorses 2. Evaluation of the diagnostic significance of neutrophil percentage. Aust Vet J, 81, 685–687.
  • Manguin E., Pépin E., Boivin R., Leclere M. (2020). Tracheal microbial populations in horses with moderate asthma. J Vet Intern Med, 34, 986–995.
  • Moore I., Horney B., Day K. (2004). Treatment of inflammatory airway disease in young standard-breds with interferon alpha. Can Vet J, 45, 594–601.
  • Rettmer H., Hoffman A.M., Lanz S. (2015). Owner-reported coughing and nasal discharge are associated with clinical findings, arterial oxygen tension, mucus score and bronchoprovocation in horses with recurrent airway obstruction in a field setting. Equine Vet J, 47, 291–295.
  • Richard E.A., Fortier G.D., Lekeux P. M., Van Erck E. (2010). Laboratory findings in respiratory fluids of the poorly-performing horse. Vet J, 185, 115–122.
  • Riihimaki M., Raine A., Elfman L., Pringle J. (2008). Markers of respiratory inflammation in horses in relation to seasonal changes in air quality in a conventional racing stable. Can J Vet Res, 72, 432–439.
  • Robinson N.E., Berney C., Eberhart S. (2003). Coughing, mucus accumulation, airway obstruction, and airway inflammation in control horses and horses affected with recurrent airway obstruction. Am J Vet Res, 64, 550–557
  • Rossi H., Virtala A., Raekallio M., Rahkonen E., Rajamäki M., Mykkänen A. (2018). Comparison of tracheal wash and bronchoalveolar lavage cytology in 154 horses with and without respiratory signs in a referral hospital over 2009−2015. Frontiers in Veterinary Science, 5, 61
  • Sanchez A., Couetil L.L., Ward M.P., Clark S.P. (2005). Effect of airway disease on blood gas exchange in racehorses. J Vet Intern Med, 19, 87–92.
  • Widmer A., Doherr M.G., Tessier C. (2009). Association of increased tracheal mucus accumulation with poor willingness to perform in show-jumpers and dressage horses. Vet J, 182, 430–435