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Published February 23, 2023 | Version 4.0.5

biobakery/MetaPhlAn: 4.0.5

  • 1. University of Trento
  • 2. Weill Cornell Medicine
  • 3. Okinawa Institute of Science and Technology
  • 4. University of Freiburg
  • 5. INRA MetaGenoPolis
  • 6. Edmund Mach Foundation

Description

Version 4.0.5 (Feb 23rd, 2023) Database updates
  • We just released the new vOct22 database
  • Addition of ~200k new genomes
  • 3,580 more SGBs than the vJan21
  • 2,548 genomes considered reference genomes in vJan21 were relabelled as MAGs in NCBI -> 1,550 kSGBs in vJan21 are now uSGBs in vOct22
  • Removed redundant reference genomes from the vJan21 genomic database using a MASH distance threshold at 0.1%
  • Local reclustering to improve SGB definitions of oversized or too-close SGBs
  • Improved GGB and FGB definitions by reclustering SGB centroids from scratch
  • Improved phylum assignment of SGBs with no reference genomes at FGB level using MASH distances on amino acids to find the closest kSGB ### Changed features
  • [StrainPhlAn] Improved StrainPhlAn's speed when running with the --print_clades_only option ### Missing features
  • [MetaPhlAn] The GTDB taxonomic assignment for the vOct22 database is not available yet (expected release: end of Feb 2023)
  • [MetaPhlAn] The phylogenetic tree of life for the vOct22 database is not available yet (expected release: TBD).

Files

biobakery/MetaPhlAn-4.0.5.zip

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