MYRAMISTIN AS AN ANTISEPTIC AND DISINFECTANT

Nowadays, the rapid growth of resistance of pathogens of nosocomial infections to disinfectants and antiseptics forces the list of drugs in this group to be increasingly expanded. The aim is to summarize the data of literary sources regarding the peculiarities of the use of myramistin as an active pharmaceutical ingredient (API) in the medical field, in particular, in the pharmaceutical industry, with the aim of developing and expanding the range of disinfectant medicinal products in various forms of release. Myramistin is an API for local use with a wide spectrum of antibacterial action, and is widely used in surgery, traumatology, obstetrics, dermatovenerology, combustiology, otorhinolaryngology and stomatology. Microbiological action is aimed at suppressing and destroying populations of gram-positive, gram-negative, aerobic and anaerobic microorganisms, including those resistant to antibiotics, in the centers of the infectious agent of the skin, mucous membranes, and serous cavities. The mechanism of myramistin's antimicrobial action is justified by its belonging to quaternary ammonium compounds characterized by the specificity of its antimicrobial action. Supplementing the assortment of medicines, expanding possible indications for the use of myramistin in clinical areas based on its already known properties are promising goals of medicine and pharmacy as a whole.