Published December 1, 2022 | Version v1
Dataset Open

Mice infected with Low shedder S. mansoni parasites from cross A - cage 1 - Liver histopathology data.

  • 1. Texas Biomedical Research Institute
  • 2. Texas Biomedical Research Institute, UT Health, Microbiology, Immunology & Molecular Genetics

Description

The present dataset contains all the histopathology images used to quantify fibrotic areas, parasite egg counts and to quantify granuloma areas in liver of mice infected with S. mansoni Low shedder line. These data are presented in the manuscript entitled "No evidence for schistosome parasite fitness trade-offs in the intermediate and definitive host" (dataset # 4/11).
Each folder corresponds to one mouse sample and contain, along with a readme file, all the files used to quantify fibrotic area and egg counts (_TRICH.czi), to quantify granuloma area (_HE.czi), and the annotation file (.annotations) containing all the annotated granuloma areas.

Notes

We generated and used 11 datasets for this manuscript. - 1 dataset containing all the phenotype data collected and R scripts used for data analysis, and to generated the figures (Figures 2 to 5) present in the manuscript. - 10 larger datasets containing all the histopathology images of infected and control mice. These datasets have been uploaded separately, due to their size, and numbered 2-11/11.

Files

1AL_dataset.zip

Files (35.9 GB)

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Additional details

Funding

National Institutes of Health
Genetic analysis of cercarial release in schistosomes 5R01AI133749-02