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Published November 22, 2022 | Version v1
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Hybrid Sequencing of Staphylococcus aureus from Chronic Rhinosinusitis Patients Reveals Widespread Beta-Lactamase Plasmids Associated with Chromosomal Varation in Virulence Genes

Authors/Creators

  • 1. The University of Adelaide

Description

Staphylococcus aureus isolates colonising the sinuses of patients with CRS commonly carry extra-chromosomal plasmids harbouring beta-lactamase genes. Those plasmids associate with chromosomal mutations in virulence genes that may be involved in mediating chronic inflammation. 

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