Activation patterns of afferent synapses on layer 5 tufted pyramidal cells in a biologically detailed simulation

The data set is based on a biologically detailed simulation of a circuit of cortical neurons. The circuit was activated by thalamo-cortical inputs every 1 s for 500 ms. We report for a number of exemplary tufted pyramidal cells in layer 5 the pattern activation of their afferent synapses.

Specifically, we report for all afferent excitatory synapses the pairwise path distances along the dendrite / soma (note that the soma was simplified to a point for the purpose of calculating path distances, but not during the simulation), and the times of activation of each of these synapses.

The simulation is based on the model described in this preprint. The model can also be found here on Zenodo. For more details on the simulation, contact the author.

For more details about the format of the data, refer to the included jupyter notebook.