Published August 2, 2022
| Version v2
Journal article
Open
RNA sequencing of A2780 cells treated with CCL2 identified genes associated with A2780 cell growth
Description
Exogenous CCL2 promotes A2780 cell activity. RNA sequencing was used to identify the transcriptomic changes in CCL2-treated A2780 cells. Based on |log2 Fold Change| > 1 and and p < 0.05, 190 differentially expressed genes were selected. Of these genes, 82 were observed to be upregulated and 108 downregulated.The gene ontology analysis of differentially-expressed genes was performed to identify the underlying functions and biological processes. In addition, the expression of the topmost upregulated genes was verified by qPCR.
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