Published October 19, 2022 | Version V1.0
Project deliverable Open

AESI Case Definition Companion Guide: Multisystem Inflammatory Syndrome In Children and Adults (MIS-C/A)


  • 1. SPEAC


This document collates into a single document the SPEAC MIS-C/A resources (ICD9/10-CM, MedDRA and SNOMEDCT codes), tools (data abstraction & interpretation form, tabular summary of key case definition criteria and algorithm for level of certainty determination, pictorial level of certainty algorithm) and guidance (real time investigation, data collection, analysis, and presentation). This guide can be used by stakeholders to assess the occurrence of MIS-C/A in several settings including as an adverse event following immunization.


The SPEAC project is funded in whole by CEPI.


SPEAC_D2.5.2.1_MIS-C_A Companion Guide_V0.1_13_Oct_2022_BL rev (1).pdf

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