Modeling and Analysis of a Wirelessly Powered Closed-Loop Implant for Epilepsy

Abstract

A system-level model of a wireless power and data transmission system with a closed-loop epileptic seizure detector and suppressor device for low-power implantable applications is proposed using the MATLAB Simulink software. The proposed system transmits power and bidirectional data through a single inductive link with a monitoring unit, and records high-resolution intracranial-EEG (iEEG) signals by multiple electrode channels. The recording signals are processed in the analog domain and feed a digital signal processing block to extract five time-domain features to detect the seizure onsets, using datasets from Inselspital Bern. Subsequently, a current-mode multi-channel electrical stimulator is activated according to the seizure detection signal and delivers the electrical pulses to the brain.

How to use

System Simulink file can be opened in MATLAB Simulink and the whole system can be found. Or, the script of Controlled.m can be opened, the initial parameter should be given and after clicking on the Run button, the system-level modeling simulation results are shown in the separate figures.

Publication

These system-level models are used in the following conference paper:

System-Level Modeling of a Safe Autonomous Closed-loop Epileptic Seizure Control Implant

Funding source

This project has been supported by the SNSF under project No. 200020-18254