Convergent genomics of longevity in rockfishes highlights the genetics of human lifespan variation

Longevity is a defining, heritable trait that varies dramatically between species. To resolve the genetic regulation of this trait, we have mined genomic variation in rockfishes, which range in longevity from 11 to over 205 years, along with the sea robin as an outgroup. We used the phylomapping methodology to target sequencing and assembly to conserved, functional loci, defined using available genomic resources from well-characterized species. These annotations are in the gtf. For analysis of coding elements, assembled contigs were trimmed to just the exons. Exons were concatenated and analyzed to generate gene trees with IQTree, fixed to match the species tree. Additional details of these assembly methods are available at DOI: 10.1038/s41559-019-0914-2 and DOI: 10.1126/sciadv.add2743