Published May 3, 2021 | Version 1.3
Dataset Open

REVEL (Rare Exome Variant Ensemble Learner) Scores

  • 1. Icahn School of Medicine at Mount Sinai

Description

REVEL is an ensemble method for predicting the pathogenicity of missense variants in the human genome.  For more information, see https://sites.google.com/site/revelgenomics/ and https://dx.doi.org/10.1016/j.ajhg.2016.08.016.

Files

revel-v1.3_all_chromosomes.zip

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Additional details

Related works

Is described by
Journal article: 10.1016/j.ajhg.2016.08.016 (DOI)

References

  • Ioannidis NM, Rothstein JH, Pejaver V, Middha S, McDonnell SK, Baheti S, Musolf A, Li Q, Holzinger E, Karyadi D, Cannon-Albright LA, Teerlink CC, Stanford JL, Isaacs WB, Xu J, Cooney KA, Lange EM, Schleutker J, Carpten JD, Powell IJ, Cussenot O, Cancel-Tassin G, Giles GG, MacInnis RJ, Maier C, Hsieh CL, Wiklund F, Catalona WJ, Foulkes WD, Mandal D, Eeles RA, Kote-Jarai Z, Bustamante CD, Schaid DJ, Hastie T, Ostrander EA, Bailey-Wilson JE, Radivojac P, Thibodeau SN, Whittemore AS, and Sieh W. "REVEL: An ensemble method for predicting the pathogenicity of rare missense variants." American Journal of Human Genetics 2016; 99(4):877-885