Published September 9, 2022
| Version v1
Dataset
Open
Locus Coeruleus firing patterns selectively modulate brain activity and dynamics
Creators
- 1. EPFL, ETH Zurich
- 2. ETH Zurich
- 3. University of Sydney
-
4.
Friedrich Miescher Institute
-
5.
Sorbonne Université
- 6. University of Zurich
- 7. ETH Zurich, University of Zurich
-
8.
University of Geneva
Description
This dataset supports the manuscript entitled 'Locus Coeruleus firing patterns selectively modulate brain activity and dynamics' (https://doi.org/10.1101/2022.08.29.505672). Please refer to this manuscript for detailed information.
The dataset contains a total of 81 functional (GE-BOLD) and 30 anatomical (T1-weighted) scans of ChR2-expressing C57BL/6-Tg(Dbh-iCre)1Gsc mice in NIFTI format, multiplied by 10. Mice were optogenetically stimulated with blue light in the right Locus Coeruleus in a 3Hz tonic, 5Hz tonic, and 15Hz burst pattern. Sham stimulation entailed red light stimulation at a 5Hz tonic frequency. The 'StimulationProtocol' text file specifies the precise onset (in seconds, minus 10 seconds for dummy scans) and duration (in seconds) of the different optogenetic stimulation protocols during a 1440 seconds functional scan. The 'SubjectDetails' file lists the subject IDs, their gender, their genotype, the stimulation type of functional scans, and their associated anatomical scan.
Files
Opto_LC_15Hzburst.txt
Files
(21.0 GB)
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