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Published August 26, 2022 | Version v0.7.1
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ctboughter/AIMS: AIMS_0.7.1

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Description

Note, this release only has minor updates from v0.7, making the mhc_germline_analysis more user-friendly

This release is primarily meant to accompany the new manuscript "A Systematic Characterization of Germline-Encoded Contacts Identifies the Source of Bias in TCR-MHC Interactions", guaranteeing that readers of this manuscript can exactly recreate the analysis used to generate each figure. However, these updates also provide significant resources for new approaches to the analysis of TCR-MHC interactions (a future research direction).

New Updates Include: Changes to the aims_analysis.py file for MHC germline associated functions Changes to the aims_loader.py file for MHC germline associated functions A new notebook: mhc_germline_analysis.ipynb which gives a step-by-step instructions for recreating the analysis New directory "germline_data" added for data downloaded via IMGT and reformatted for AIMS

In addition to the updates outlined here, related raw data for this MHC germline analysis which are too large to upload to this page have been uploaded to Zenodo. Check out the manuscript and the ReadTheDocs for links to this data [not yet uploaded at the time of this release].

The GUI has not been updated to include these features, and still includes the known issues listed in v0.6. GUI updates will continue in the coming months.

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ctboughter/AIMS-v0.7.1.zip

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