Published July 16, 2022
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Microarray detail DNA repair genes
Description
Up and down gene expression between non-obstructive azoospermia and normal case by microarray:
We evaluated all The DNA repair genes (322 genes) by microarray. This study has provided insight into the connection between DNA repair genes, including RAD23B, OBFC2A, PMS1, UBE2V1, ERCC5, SMUG1, RFC4, PMS2L5, MMS19, SHFM1, INO80, PMS2L1, CHEK2, TRIP13, and POLD4. The microarray analysis of five human cases with different non-obstructive azoospermia revealed that RAD23B, OBFC2A, PMS1, UBE2V1, ERCC5, SMUG1, RFC4, PMS2L5, MMS19, SHFM1and INO80 were up-regulated, and expression of PMS2L1, CHEK2, TRIP13, and POLD4 was down-regulated with the normal case.
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