AneuX morphology database

The AneuX morphology database is an open-access, multi-centric database containing 3D geometries of 750 intracranial aneurysms curated in the context of the AneuX project (2015-2020). The database combines data from three different projects (AneuX, @neurIST and Aneurisk) standardized using a single processing pipeline. The code to process and view the 3D geometries is provided under this public repository: https://github.com/hirsch-lab/aneuxdb

The database at a glance:

• 750 aneurysm domes (surface meshes)
• 668 vessel trees (surface meshes)
• 3 different data sources (AneuX, @neurIST, Aneurisk)
• 3 different mesh resolutions (original resolution, 0.01mm² and 0.05mm² target cell area)
• 4 different cut configurations (including planar and free-form cuts)
• 5 clinical parameters (aneurysm rupture status, location and side; patient age and sex)
• 170 pre-computed morphometric indices for each of the aneurysm domes

Terms of use / License:

The data is provided "as is", without any warranties of any kind. It is provided under the CC BY-NC 4.0 license, with the additional requirements (A) that the use of the database is declared using the sentence below (you can omit the URLs), and (B) to cite our peer reviewed journal article below.

[This project] uses data from the AneuX morphology database, an open-access, multi-centric database combining data from three European projects: AneuX project (www.aneux.ch), @neurIST project (www.aneurist.org) and Aneurisk (http://ecm2.mathcs.emory.edu/aneuriskweb/index).

In accordance with the terms of use, please cite the following journal article when referring to our dataset.

Juchler, Schilling, Bijlenga, Kurtcuoglu, Hirsch. Shape trumps size: Image-based morphological analysis reveals that the 3D shape discriminates intracranial aneurysm disease status better than aneurysm size. Frontiers in Neurology (2022), DOI: 10.3389/fneur.2022.809391

The AneuX morphology database contains parts (geometric models, clinical data) of the publicly available Aneurisk dataset released under the CC BY-NC 3.0 license (which is compatible with the license used here). Like all geometric models in this database, the Aneurisk models were preprocessed using the same procedure. See here for a description.

Funding and authorizations 

• The AneuX project
• Data collection in accordance with @neurIST protocol v5
• Ethics autorisations Geneva BASEC PB_2018‐00073
• Supported by the grant from the Swiss SystemsX.ch initiative, evaluated by the Swiss National Science Foundation
• @neurIST project
• Data collection in accordance with @neurIST protocol v1
• Ethics autorisations AmsterdamMEC 07-159, Barcelona2007-3507, Geneva CER 07-056, Oxfordshire REC AQ05/Q1604/162, Pècs RREC MC P 06 Jul 2007
• Supported by the 6th framework program of the European Commission FP6-IST-2004–027703

Acknowledgments:

The AneuX project was supported by SystemsX.ch, and evaluated by the Swiss National Science Foundation (SNSF). This database would not be possible without the support of the Zurich University of Applied Sciences (ZHAW) and University Hospitals Geneva (HUG).

We thank the following people for their support and contributions to the AneuX morphology database.

From the AneuX project (in alphabetical order):

• Daniel Rüfenacht
• Diana Sapina
• Isabel Wanke
• Karl Lovblad
• Karl Schaller
• Olivier Brina
• Paolo Machi
• Rafik Ouared
• Sabine Schilling
• Sandrine Morel
• Ueli Ebnöther
• Vartan Kurtucuoglu
• Vitor Mendes Pereira
• Zolt Kuscàr

From the @neurIST project (in alphabetical order)

• Alan Waterworth
• Alberto Marzo
• Alejandro Frangi
• Alison Clarke
• Ana Marcos Gonzalez
• Ana Paula Narata
• Antonio Arbona
• Bawarjan Schatlo
• Daniel Rüfenacht
• Elio Vivas
• Ferenc Kover
• Gulam Zilani
• Guntram Berti
• Guy Lonsdale
• Istvan Hudak
• James Byrne
• Jimison Iavindrasana
• Jordi Blasco
• Juan Macho
• Julia Yarnold
• Mari Cruz Villa Uriol
• Martin Hofmann-Apitius
• Max Jägersberg
• Miriam CJM Sturkenboom
• Nicolas Roduit
• Pankaj Singh
• Patricia Lawford
• Paul Summers
• Peer Hasselmeyer
• Peter Bukovics
• Rod Hose
• Roelof Risselada
• Stuart Coley
• Tamas Doczi
• Teresa Sola
• Umang Patel

From the Aneurisk project (list from AneuriskWeb, in alphabetical order):

• Alessandro Veneziani
• Andrea Remuzzi
• Edoardo Boccardi
• Francesco. Migliavacca
• Gabriele Dubini
• Laura Sangalli
• Luca Antiga
• Maria Piccinelli
• Piercesare Secchi
• Simone Vantini
• Susanna Bacigaluppi
• Tiziano Passerini