Published June 7, 2022
| Version v1
Dataset
Open
Uncovering the molecular basis for the better Gefitinib sensitivity of EGFR with complex mutations over single rare mutation: insights from molecular simulations
Creators
- 1. Nanjing Agricultural University
- 2. Macao Polytechnic University
Description
Molecular Dynamics trajectories and topology files of APO and Gefitinib(IRE)-bound Epidermal growth factor receptor (EGFR) mutants: rare (G719S), rare + rare (G719S/L861Q) and rare + classical (G719S/L858R). The trajectories presented in this work were analyzed and presented in "Uncovering the molecular basis for the better Gefitinib sensitivity of EGFR with complex mutations over single rare mutation: insights from molecular simulations".
Files
Files
(8.6 GB)
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md5:9467988ca6f6a5d79101269608838596
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479.0 MB | Download |
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485.2 MB | Download |
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484.0 MB | Download |
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md5:861e854ba195c173addeb2db4c6c279f
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479.0 MB | Download |
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2.2 MB | Download |
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md5:652428b895ea5d7a65e5d45cd09f98a9
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483.9 MB | Download |
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485.3 MB | Download |
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md5:cd26bd22f1e70a13fba36ee582926937
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2.2 MB | Download |