Crosstalk between imbalanced gut microbiota caused by antibiotics and rotavirus replication in the intestine

In this manuscript, we discover that 10% of young adults are asymptomatic rotavirus infected. Imbalanced gut microbiota caused by veterinary antibiotics and preferred as veterinary antibiotics play an important role in this situation. High level of lipopolysaccharide produced by gram-negative bacteria promote rotavirus replication. Our results demonstrated that patients have a disrupted gut microbiota following rotavirus infection, and therefore may be at risk for long-term health complications. We believe that our findings widen the knowledge about the infection of rotavirus.