Published May 10, 2022
| Version v1
Poster
Open
Multiscale modeling of the yeast mitofusin Fzo1
Authors/Creators
- 1. Laboratoire de Biochimie Theorique - UPR9080
Description
Mitochondria are dynamic organelles whose ultrastructural organization is essential in maintaining their quality control and ensuring functional efficiency. The mitochondrial network is the result of both fusion and fission of inner and outer membranes.
Tethering and homotypic fusion of mitochondrial outer membranes is mediated by large GTPases of the dynamin-related proteins family called the mitofusins. Their full-length structures remain unknown, which is a limiting factor in the study of outer membrane fusion.
Files
Poster_Fzo1 (2).pdf
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(3.7 MB)
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Additional details
Funding
- Agence Nationale de la Recherche
- DYNAMO - Dynamique des membranes transductrices d'énergie : biogénèse et organisation supramoléculaire. 11-LABX-0011
- Agence Nationale de la Recherche
- MITOFUSION - Structure, Assembly and Biophysical Properties of Mitofusins ANR-19-CE11-0018