Published April 20, 2022
| Version v1
Dataset
Open
Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity; Data sets
Creators
-
Minee L. Choi1
- Alexandre Chappard
- Bhanu P. Singh
- Catherine Maclachlan
- Margarida Rodrigues
- Evgenia Fedotova
- Alexey V. Berezhnov
- Suman De
- Chris Peddie
- Dilan Athauda
- Gurvir S. Virdi
- Weijia Zhang
- James R. Evans
- Plamena R. Angelova
- Noemi Esteras
- Katie Morris
- Laura Tosatto
- Daniel Little
- Paul Gissen
- Lucy Collinson
- David Klenerman
- Andrey Y. Abramov
- Mathew H. Horrocks
- Sonia Gandhi
- 1. UCL Queen Square Institute of Neurology
Description
Lists of data sets included in "Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity"
Single-molecule confocal Quantification_Images (SNCA-A53T TIRF Images)
TIRF Image Quantification
TIRF Emission Data
Single Vesicle Emission Data
DLS Emission Data
CD Measurements
Amyloid Fibril TIRFM Emission Data
α-Syn WT, A53T, A30P and E46K Confirmatory LCMS
SNCA A53T iPSC mutation confirmatory Sanger Sequencing
ELISA
Immunocytochemistry (MAP2 and TRB1)
Pierce BCA Protein Assay
Aggregation Assay
Copy of Empiar_upload_info (CLEM quantification); metadata spreadsheet for TEM and FIB-SEM Image Quantification
Live-cell imaging data
- Superoxide Emission Data
- MitoTracker® Red Emission Data
- MembranePotentialEmissionData (the same experiment for ' TMRM Emission data')
- Ca 2+ Emission Data
- NADH Autofluorescence and Redox Quantification
- ATP Emission Data
- mPTP Emission Data
- Cell Death Emission Data (PI & SYTOX)
- FRET Emission Data
- MitoTracker® Red Assay
- Cell Death Assay
Files
Files
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