Studies in Heterocyclic Compounds. Part XVIII. Synthesis of 3, 5-diaryl-4-(N-substituted p-sulphamylbenzeneazo) pyrazoles as potential antibacterials

Department of Chemistry, University of  Delhi, Delhi-110007

Manuscript received 14 October 1976, revised 17 January 1977, accepted 20 January 1977

In a search for new antibacterials, some 3-(\({m}\)/\({p}\)-nitrophenyl)-5-p-toluyl-4-(N-substituted p-sulphamylbenzeneazo) pyrazoles have been synthesised by condensing 1-(\({m}\)/\({p}\)-nitrophenyl)-3-\({p}\)-toluyl-2-(N-substituted p-sulphamylbenzeneazo) propane-1, 3-diones with a number of carbonyl reagents. On testing in vitro against S. aureus and E. Coli encouraging results were obtained.