Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters

Hrytsak Myroslava V., Popovych Dariya V., Ruzhylo Sofiya V., Zakalyak Nataliya R., Zukow Walery. Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters. Journal of Education, Health and Sport. 2022;12(3):274-282. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.03.023

https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.03.023

https://zenodo.org/record/6404397

The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343.

Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).

Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.

Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).

© The Authors 2022;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

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Received: 10.03.2022. Revised: 26.03.2022. Accepted: 01.04.2022.

Neuro-endocrine mechanism of specific balneoeffects of sulfate-chloride sodium-magnesium mineral waters

Myroslava V. Hrytsak^1,2, Dariya V. Popovych³, Sofiya V. Ruzhylo⁴,

Nataliya R. Zakalyak⁴, Walery Zukow⁵

¹SE Ukrainian Research Institute of Medicine of Transport, Odesa prof.gozhenko@gmail.com

²Scientific group of Balneology of Hotel&Spa Complex "Karpaty", Truskavets’, Ukraine      hrytsak.myroslava@gmail.com  ira_barschyk@ukr.net

³IY Horbachevs’kyi National Medical University, Ternopil’, Ukraine  darakoz@yahoo.com

⁴Ivan Franko Pedagogical University, Drohobych, Ukraine doctor-0701@ukr.net

⁵Nicolaus Copernicus University, Torun, Poland   w.zukow@wp.pl

Background. Earlier we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters “Myroslava” (5 g/L) and “Khrystyna” (10 g/L) have favorable effects on neuroendocrine-immune complex and metabolism of patients with their violations. At the same time, the influence of both waters on one constellation of parameters is similar, despite the twofold difference in mineralization, while on the other constellation it is different. The aim of this study was to elucidate the neuroendocrine mechanism of specific effects. Materials and Methods. The object of clinical-physiological observation were 22 men aged 23-70 years, who underwent rehabilitation treatment of chronic pyelonephritis and cholecystitis in remission in the Truskavets’ spa. The examination was performed twice, before and after a 7-10-day course of balneotherapy. All patients received bioactive water Naftussya, however, 11 men additionally drank water "Khrystyna", and the other 11 men - water "Myroslava". The subject of the study were the parameters of the neuroendocrine-immune complex and metabolism. Results. The method of canonical analysis shows that the changes in neuroendocrine factors (LF and VLF bands HRV; beta- and delta-rhythm-generating nerve structures, cortisol and aldosterone determine changes in the parameters of immunity, microbiota, metabolism and cholekinetics by 99,5-98,6%. Conclusion. The primary effects of mineral waters are the modulation of the activity of the structures of the central and autonomic nervous and endocrine systems, which, in turn, have a regulatory modulating effect on the immune system, microbiota, metabolism, cholekinetics and blood pressure.

Keywords: sulfate-chloride sodium-magnesium drinking mineral waters, Truskavets’ spa, EEG, HRV, endocrine, immune, metabolic parameters, relationships.