Published July 2, 2021 | Version v1

A deep look into radiomics

  • 1. Academic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, Italy
  • 2. CNR-IFAC Institute of Applied Physics "N. Carrara", 50019 Sesto Fiorentino, Italy
  • 3. Academic Radiology, Department of Surgical, Medical, Molecular Pathology and Emergency Medicine, University of Pisa, Via Roma 67, 56126 Pisa, Italy
  • 4. Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), Monserrato (Cagliari),Cagliari, Italy
  • 5. Academic Radiology, Department of Translational Research, University of Pisa, Via Roma 67, 56126 Pisa, Italy - Italian Society of Medical and Interventional Radiology, SIRM Foundation, Via della Signora 2, 20122 Milano, Italy

Description

Radiomics is a process that allows the extraction and analysis of quantitative data from medical images. It is an evolving field of research with many potential applications in medical imaging. The purpose of this review is to offer a deep look into radiomics, from the basis, deeply discussed from a technical point of view, through the main applications, to the challenges that have to be addressed to translate this process in clinical practice. A detailed description of the main techniques used in the various steps of radiomics workflow, which includes image acquisition, reconstruction, pre-processing, segmentation, features extraction and analysis, is here proposed, as well as an overview of the main promising results achieved in various applications, focusing on the limitations and possible solutions for clinical implementation. Only an in-depth and compre- hensive description of current methods and applications can suggest the potential power of radiomics in fostering precision medicine and thus the care of patients, especially in cancer detection, diagnosis, prognosis and treatment evaluation

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Additional details

Funding

European Commission
ProCAncer-I - An AI Platform integrating imaging data and models, supporting precision care through prostate cancer’s continuum 952159
European Commission
PRIMAGE - PRedictive In-silico Multiscale Analytics to support cancer personalized diaGnosis and prognosis, Empowered by imaging biomarkers 826494
European Commission
CHAIMELEON - Accelerating the lab to market transition of AI tools for cancer management 952172
European Commission
EuCanImage - A European Cancer Image Platform Linked to Biological and Health Data for Next-Generation Artificial Intelligence and Precision Medicine in Oncology 952103