A computational model of the Src kinase pathway in hypoxic neonatal brain injury

This file is a MATLAB SimBiology project file that contains the "Kratimenos_et_al_CaM-Src_model" model. This file can be used to launch and simulate the SimBiology computational model accompanying the manuscript:

"Computational Analysis of Cortical Neuronal Excitotoxicity in a Large Animal Model of Neonatal Brain Injury"

Panagiotis Kratimenos^1,2,5 *, Abhya Vij⁵, Robinson Vidva⁶, Ioannis Koutroulis^3,4,5, Maria Delivoria-Papadopoulos⁷**, Vittorio Gallo^1,5, and Aaron Sathyanesan^1,5*

¹Center for Neuroscience Research, Children’s National Research Institute, Children’s National Hospital, Washington DC, USA

²Department of Pediatrics, Division of Neonatology, Children’s National Hospital, Washington DC, USA

³Department of Pediatrics, Division of Emergency Medicine, Children’s National Hospital, Washington, DC, USA

⁴Center for Genetic Medicine Research, Children’s National Research Institute and Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA

⁵George Washington University School of Medicine and Health Sciences, Washington DC, USA

⁶Digirobi Solutions, Bengaluru, Karnataka, India

⁷Department of Pediatrics, Drexel University College of Medicine, Philadelphia, PA, USA

*Corresponding Authors:

Panagiotis Kratimenos, MD, PhD: panagiotis.kratimenos@childrensnational.org

Aaron Sathyanesan, PhD: asathyanesan@childrensnational.org

111 Michigan Avenue, Washington, DC, 20010, USA