Published February 4, 2022 | Version v1
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Imaging of Organic Samples with Megaelectron Volt Time-of-Flight Secondary Ion Mass Spectrometry Capillary Microprobe


Time-of-flight Secondary Ion Mass Spectrometry (TOF SIMS) with MeV primary ions offers a fine balance between secondary ion yield for molecules in the mass range from 100 to 1000 Da and beam spot size, both of which are critical for imaging applications of organic samples. Using conically shaped glass capillaries with an exit diameter of a few micrometers, a high energy heavy primary beam can be collimated to less than 10 μm. In this work, imaging capabilities of such a setup are presented for some organic samples (leucine-evaporated mesh, fly wing section, ink deposited on paper). Lateral resolution measurement and molecular distributions of selected mass peaks are shown. The negative influence of the beam halo, an unavoidable characteristic of primary beam collimation with a conical capillary, is also discussed. A new start trigger for TOF measurements based on the detection of secondary electrons released by the primary ion is presented. This method is applicable for a continuous primary ion beam, and for thick targets that are not transparent to the primary ion beam. The solution preserves the good mass resolution of the thin target setup, where the detection of primary ions with a PIN diode is used for a start trigger, reduces the background, and enables a wide range of samples to be analyzed.


M. Brajković acknowledges support by the Croatian Science Foundation (CSF) project "Young Researchers' Career Development Project - Training of Doctoral Students" cofinanced by the European Union, Operational Program "Efficient Human Resources 2014-2020" and the ESF. I. B. Radovic. and Z. Siketic ́ ́ acknowledge support by the CSF project IP-2016-06-1698 "Development of a capillary microprobe for MeV SIMS for analysis of biological materials− BioCapSIMS" and by the RADIATE project under the Grant Agreement 824096 from the EU Research and Innovation program HORIZON 2020. The authors also acknowledge financial support from the European Regional Development Fund for the 'Center of Excellence for Advanced Materials and Sensing Devices' (Grant No. KK.


imaging article

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RADIATE – Research And Development with Ion Beams – Advancing Technology in Europe 824096
European Commission